> Panloc®

Composition :
Pantoprazole 40 mg

Indication :

• Moderate to severe esophagitis reflux.
• Pathological hypersecretion therapy related with Zollinger-Ellison syndrome or other malignancy.

Dosage and Administration :

• Gastroesophageal Reflux Disease Associated With a History of erosive esophagitis.

The recommended adult dose is 40 mg Pantoprazole given once daily by intravenous infusion for 7 to 10 days.

• Zollinger-Ellison Syndrome.

The recommended adult dosage for Zollinger-Ellison Syndrome is 80 mg q12h. The frequency of dosing can be adjusted to individual patient needs based on acid output measurements.

Instruction for Use :
A ready-to-use solution is prepared by injecting 10 ml of physiological sodium chloride solution into the vial containing the dry substance. This solution may be administered directly or may be administered after mixing with 100 ml physiological sodium chloride solution or 5% Glucose. After preparation the solution must be used within 12 hours. From a microbiological point of view, the product should be used immediately. If not used immediately, normally not be longer than 12 hours at not more than 25OC.

Contraindications :
Patients with known hypersensitivity to the formulation.

Drug Interactions :

• Pantoprazole is metabolized through the cytochrome P450 system.
• No dosage adjustment is needed with concomitant use of the following : theophylline, cisapride, antipyrine, caffeine, carbamazepine, diazepam, diclofenac, naproxen, piroxicam, digoxin, ethanol, glyburide, an oral contraceptive (levonorgestrel/ethinyl estradiol), metoprolol, nifedipine, phenytoin, warfarin (see below), midazolam, clarithromycin, metronidazole, or amoxicillin.
• There is no drug interaction with antacid.
• There have been postmarketing reports of increased INR and prothrombin time in patients receiving proton pump inhibitors, including pantoprazole, and warfarin concomitantly. Increases in INR and prothrombin time may lead to abnormal bleeding and even death. Patients treated with proton pump inhibitors and warfarin concomitantly should be monitored for increases in INR and prothrombin time.

Presentation :
Box,1 vial @ 40 mg active ingredient.

> LIVOLA® Infus

Composition :
Each ml infusion contains : L-ornithine L-aspartate 500 mg

Indication :
For reducing plasma ammonia level in condition of hyperammonemia as a result of acute and chronic liver desease such as liver cirrhosis, fatty liver, hepatitis, especially in the treatment of incipient disturbance of consciousness (pre coma) or neurological complications (Hepatic encephalopathy).

Presentation :
Box, 5 ampoules @ 10 ml.

> Recustein®

Composition :
-    Each capsule contains : Erdosteine 300 mg
-    Each 5 ml syrup contains : Erdosteine 175 mg

Indications :  Mucolytic,  fluidifying agent in acute and chronic airways affections. 

Dosage and administration :
-    Capsule : 2-3 times a day
-    Syrup for children :
     15  – 19 kg : 5 ml 2 times daily
     20  – 30 kg : 5 ml 3 times daily
        > 30 kg    : 10 ml 2 times daily

Presentation :
-    Box, 2 strips @ 10 capsules
-    Box, bottle @ 60 ml

> Molinfa®

Composition :
Each soft capsule contains  multivitamins-minerals enriched with Choline bitartrate & DHA - essential nutrients for brain development of fetus & infant.

Usage : Once daily

Presentation : box 3 x 10’s

> COPIDREL®

Composition :
Each film coated tablet contains Clopidogrel bisulfate 97.875 equivalent to Clopidogrel 75 mg

Pharmacology :
Clopidogrel is an inhibitor of platelet aggregation. It selectively inhibits the binding of adenosine diphosphate (ADP) to its platelet receptor and the subsequent ADP-mediated activation of the glycoprotein GPIIb/IIIa complex, thereby inhibiting platelet aggregation.
Platelet aggregation and bleeding time gradually return to baseline values after treatment is discontinued, generally in about 5 days.                                     

Indication :
-    Myocardial Infarction (MI), Ischaemic Stroke, Peripheral Arterial Disease (PAD).
-    Acute Coronary Syndrome (ACS)

Dosage and Administration :
Adults and elderly : Single daily dose of 75 mg with or without food.

Presentation :
Box, 3 strips @ 10 film coated tablets.

> PLASMIN®

PLASMIN^® is agent, which is sourced from soil dragon (lumbricus) extracts. It is processed by high technology that generates 3 (three) enzymes as active ingredients. It has the capability of dissolving old and new thrombus.

PLASMIN^® Bottle

• 250 mg per capsule
• 180 coated enteric capsule

PLASMIN^® Box

• 250 mg per capsule
• 36 coated enteric capsule

PLASMIN^® is packed into coated enteric capsule that contains

• Enzyme fibrinolysin
• Enzyme profibrinolysin activator
• Enzyme collagenase

Indication
PLASMIN^® is indicated for supporting dissolution of fibrin and thrombus, improving blood circulation, solubilizing hemostasis, preventing platelet coagulation, and reducing blood viscosity, which can be used for preventive and curative treatment on ischaemic stroke or for people having risk factor of ischaemic stroke such as having the following diseases :

• Hyperlipidemia
• Hypertension
• Diabetes

Dosage
For treatment : 3 times a day, 2 or 3 capsules each time, taking haft an hour before meal.
For prevention : 2 times a day, 2 capsules each time, taking half an hour before meal.

Caution

• For cerebral haemorrhage occurred or under doctors suggestion.
• Pregnancy, and during the period of menses should not take it or as recommended by doctors.
• Stop use this drug 10 days before surgery.

> LEXA®

LEXA^® an oral fluoroquinolone, is the optical S (-) isomer of ofloxacin which has a wide spectrum antibacterial effect. The main mechanism of action is through the inhibition of DNA gyrase resulting in inhibition of bacterial DNA replication and transcription. Lexa is especially penetrates well into long tissue and other tissues.

LEXA^® F.c. Caplet
• Levofloxacin 500 mg, f.c.Caplet (1x10’s)

LEXA^® Infusion
• Levofloxacin 500 mg, bottle (100 ml)
• Levofloxacin 750 mg, bottle (150 ml)

LEXA^® is indicated for infections caused by susceptible microorganisms such as :
- Acute maxillary sinusitis,
- Community acquired pneumoniae,
- Acute bacterial exacerbations of chronic bronchitis,
- Complicated urinary tract infections,
- Acute pyelonephritis,
- Uncomplicated skin and skin structure infections.

LEXA^®is recommended dosage is 250 – 500 mg once daily for 7 – 14 days.

LEXA^® is contraindicated for patients with hypersensitivity to quinolone antibiotics, pregnant and nursing women, and children or adolescents less than 18 years.

ATTENTION:
CNS stimulation and photosensitivity have been reported in patients receiving this drug. May impaired the ability to drive or operate machines. The safety and efficacy of Levofloxacin in pregnant and nursing women and children have not been established.

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